Fmoc-Glu(OtBu)-OH; Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9

Fmoc-Glu(OtBu)-OH; Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9

  • Catalogue No.: 36806
  • Product Name: Fmoc-Glu(OtBu)-OH
  • Synonyms: Fmoc-L-glutamic acid 5-tert-butyl ester
  • CAS: 71989-18-9
  • EC: 276-253-8
  • MDL: MFCD00037135
  • ————————————————–
  • Price: $2500/5kg
  • Price(bulk): Inquiry Us

Properties

Assay: 98.0%
Appearance: white powder
Specific Rotation [20/D]: -16±2° (c=1, in DMF)
Melting Point: 85~95℃

Fmoc-Glu(OtBu)-OH; Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9 is the standard Fmoc-protected derivatives of Glu used in peptide synthesis. The t-butyl ester of the side chain is removed in the same conditions used to cleave peptides from Wang resin or Rink amide resin. The t-butyl cations formed in the hydrolysis of the ester can produce byproducts by reattaching to nucleophilic residues in the peptide, so nucleophilic scavengers such as thiophenol and anisole should be added to the cleavage mixture when Fmoc-Glu(OtBu)-OH are utilized.

ChemSpecial | China, wholesale Fmoc-Glu(OtBu)-OH; Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9 with high quality and good price.

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