Fmoc-Asn(Trt)-OH; Nα-Fmoc-Nγ-trityl-L-asparagine 132388-59-1

Fmoc-Asn(Trt)-OH; Nα-Fmoc-Nγ-trityl-L-asparagine 132388-59-1

Specifications

Properties

Assay 98.0%
Appearance white to off-white powder
Specific Rotation [20/D] -16.0±2.0° (c=1 in DMF)
Melting Point 201~204℃
Moisture 0.50% max
Packing 1kg/bag

Fmoc-Asn(Trt)-OH; Nα-Fmoc-Nγ-trityl-L-asparagine 132388-59-1 prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents.  Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF.  The trityl group is removed with TFA.  This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide.  In these cases, the deprotection reaction should be extended to 2 hours.

Contact us to buy wholesale Fmoc-Asn(Trt)-OH; Nα-Fmoc-Nγ-trityl-L-asparagine 132388-59-1 direct from China.

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